Plavix, Effient, Brilinta, Oh My!

With Plavix the reigning drug treatment of choice for individuals requiring antiplatelet treatment, the list of new options hoping to rival the blockbuster drug continues to grow, giving doctors and patients more choices and flexibility. With the growing number of choices, how do you know which drug is right for you? Here are some fast facts about Brilinta and, as always, the bottom line. Read on and then chat with your doctor!

Recently, the U.S. Food and Drug Administration (FDA) approved Brilinta, a new blood-thinning drug to reduce cardiovascular death and heart attack in patients with acute coronary syndromes (ACS).  Brilinta joins the ranks of other available blood-thinning agents, such as the blockbuster drug, Plavix, and the less widely prescribed, Effient.

What is ACS?

According to the FDA, ACS is a group of symptoms for a condition, such as angina or heart attack, which could result from a decrease in blood flow to the heart.

How Does Brilinta Work?

Brilinta prevents the formation of a new blood clot helping to maintain blood flow in the body and reducing the risk of another cardiovascular event.

How Does Brilinta Compare?

According to clinical studies, Brilinta was more effective than Plavix in preventing heart attacks and death. However, the advantage of Brilinta over Plavix was demonstrated with aspirin doses of 75 to 100 mg once daily. The downside of Brilinta is that it is less effective if patients take more than 100 mg of aspirin daily and it wears off faster than both Plavix and Effient.

The Bottom Line

  • Brilinta prevents the formation of blood clots that can block circulation to the heart and cause cardiovascular events
  • Maintenance dose is 90 mg twice daily
  • Administered with a low dose of aspirin
  • Brilinta can be taken with or without food
  • The most common side effects are bleeding and difficulty breathing
  • Brilinta is available in 90 mg tablets
  • Brilinta is manufactured by AstraZeneca